Saccharomyces cerevisiaeGenAge entry for TIF2 (Saccharomyces cerevisiae)

Gene information (ID: 1167)

Symbol
TIF2
Name
Translation Initiation Factor
Organism
Saccharomyces cerevisiae (AnAge)

Potential relevance to longevity and/or ageing

Observations
Replicative lifespan increased by 35% in the alpha strain and 15% in the a strain
% change in avg or median lifespan
Replicative lifespan is 15-35% higher.
Lifespan Effect
Increase
Genetic Manipulation
Deletion
Longevity Category
Anti-Longevity
Primary reference
    Observations
    Mean replicative lifespan decreased in the alpha and a strain
    Lifespan Effect
    Decrease
    Genetic Manipulation
    Deletion
    Longevity Category
    Necessary for fitness
    Primary reference
      Observations
      Mean chronological lifespan decreased in the a strain by less than 50% but more than 15%
      % change in avg or median lifespan
      Mean chronological lifespan is 15%-50% lower.
      Lifespan Effect
      Decrease
      Genetic Manipulation
      Deletion
      Longevity Category
      Necessary for fitness
      Primary reference

        Homologs in other organisms

        No homologs found

        External links

        Saccharomyces Genome Database
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        Ensembl
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        Entrez Gene
        View on Entrez Gene database (853303)
        Homologues
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        UniProt
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        Internet
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