Saccharomyces cerevisiaeGenAge entry for TDA5 (Saccharomyces cerevisiae)

Gene information (ID: 1434)

Symbol
TDA5
Name
Topoisomerase I Damage Affected
Organism
Saccharomyces cerevisiae (AnAge)

Potential relevance to longevity and/or ageing

Observations
Replicative lifespan decreased by 30% in the alpha strain
% change in avg or median lifespan
Replicative lifespan is 30% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Deletion
Longevity Category
Necessary for fitness
Primary reference

    Homologs in other organisms

    Caenorhabditis elegans
    dhs-29
    Danio rerio
    dhrs3a
    Drosophila melanogaster
    CG17121
    Homo sapiens
    DHRS3
    Mus musculus
    Dhrs3
    Rattus norvegicus
    Dhrs3
    Schizosaccharomyces pombe
    SPBC16H5.14c

    External links

    Saccharomyces Genome Database
    Search
    Ensembl
    Search
    Entrez Gene
    View on Entrez Gene database (851146)
    Homologues
    Search HomoloGene
    UniProt
    Search
    Internet
    Search Google or Search Google Scholar