Caenorhabditis elegansGenAge entry for T27F7.1 (Caenorhabditis elegans)

Gene information (ID: 652)

Symbol
T27F7.1
Name
Protein T27F7.1
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
ESCRT-3 subunit

Potential relevance to longevity and/or ageing

Observations
RNA interference decreased median lifespan by 34% in wild type animals, 42% in a daf-2 background and 37% in daf-2/daf-16 double mutants.
% change in avg or median lifespan
Median lifespan is 34% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Saccharomyces cerevisiae is present as VPS24

    Homologs in other organisms

    Danio rerio
    chmp3
    Drosophila melanogaster
    vps24
    Homo sapiens
    CHMP3
    Mus musculus
    Chmp3
    Rattus norvegicus
    Chmp3
    Saccharomyces cerevisiae
    VPS24
    Schizosaccharomyces pombe
    vps24

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (173863)
    Homologues
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    UniProt
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    Internet
    Search Google or Search Google Scholar