Drosophila melanogasterGenAge entry for Surf1 (Drosophila melanogaster)

Gene information (ID: 636)

Symbol
Surf1
Aliases
BcDNA:GH23574; CG9943; Dmel\CG9943
Name
surfeit gene 1
Organism
Drosophila melanogaster (AnAge)
Known functions and activities
A putative COX assembly factor

Potential relevance to longevity and/or ageing

Observations
Knockdown resulted in larval lethality. However, knockdown in the CNS not only bypassed the larval lethality but it resulted in an increase in maximum lifespan of about 20-30%.
% change in max lifespan
Maximum lifespan is 20-30% higher.
Lifespan Effect
Increase
Genetic Manipulation
Knockout
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Mus musculus is present as Surf1
    • A homolog of this gene for Saccharomyces cerevisiae is present as SHY1

    Homologs in other organisms

    Caenorhabditis elegans
    sft-1
    Danio rerio
    surf1
    Homo sapiens
    SURF1
    Mus musculus
    Surf1
    Rattus norvegicus
    Surf1
    Saccharomyces cerevisiae
    SHY1
    Schizosaccharomyces pombe
    shy1

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (44498)
    Homologues
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    UniProt
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    Internet
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