Mus musculusGenAge entry for Stub1 (Mus musculus)

Gene information (ID: 633)

Symbol
Stub1
Aliases
Chip; AW046544; 0610033N24Rik; 2210017D18Rik; 2310040B
Name
STIP1 homology and U-Box containing protein 1
Organism
Mus musculus (AnAge)
Known functions and activities
Involved in proteasomal degradation

Potential relevance to longevity and/or ageing

Observations
Knock-out mice exhibited a deregulation of protein quality control accompanied by a short lifespan and accelerated age-related pathophysiological features.
Lifespan Effect
Decrease
Genetic Manipulation
Knockout
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Caenorhabditis elegans is present as chn-1
    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as STUB1

    Homologs in other organisms

    Caenorhabditis elegans
    chn-1
    Danio rerio
    stub1
    Drosophila melanogaster
    CHIP
    Homo sapiens
    STUB1
    Rattus norvegicus
    Stub1

    External links

    Mouse Genome Informatics
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (56424)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
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