Mus musculusGenAge entry for Sqstm1 (Mus musculus)

Gene information (ID: 1812)

Symbol
Sqstm1
Aliases
Osi; p62; A170; STAP; OSF-6
Name
sequestosome 1
Organism
Mus musculus (AnAge)

Potential relevance to longevity and/or ageing

Observations
Knockout mice are short-lived. Males lived 34% less but females were only slightly shorter-lived. Males also exhibit signs of accelerated ageing.
% change in avg or median lifespan
Average lifespan is 34% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Knockout
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as SQSTM1

    Homologs in other organisms

    Danio rerio
    sqstm1
    Homo sapiens
    SQSTM1
    Rattus norvegicus
    Sqstm1

    External links

    Mouse Genome Informatics
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (18412)
    Homologues
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    UniProt
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    Internet
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