GenAge entry for Socs2 (Mus musculus)
Gene information (ID: 826)
- hg; JAB; CIS2; Cish2; SSI-2; SOCS-2; AI527257; AW108012; 8
- Suppressor of cytokine signaling 2
- Mus musculus (AnAge)
Potential relevance to longevity and/or ageing
- Mutant mice exhibited a reduced mean and maximal lifespan compared to wild type. The lack of SOCS2 expression in the high-growth mouse also increases plasma IGF1, and reduces plasma and pituitary GH levels.
- % change in max lifespan
- Maximum lifespan is 14% lower.
- % change in avg or median lifespan
- Average lifespan is 35% lower.
- Lifespan Effect
- Genetic Manipulation
- Longevity Category
- Primary reference
Homologs in other organisms
No homologs found