Drosophila melanogasterGenAge entry for Smox (Drosophila melanogaster)

Gene information (ID: 1904)

Symbol
Smox
Name
Smad on X
Organism
Drosophila melanogaster (AnAge)

Potential relevance to longevity and/or ageing

Observations
Post developmental RNA interference of Smox in the whole body increases lifespan by up to 10%. Tissue specific RNA interference also increases lifespan in muscle (16%) but not in adipose tissue (where it decreases lifespan).
% change in avg or median lifespan
Mean lifespan is 10% higher.
Lifespan Effect
Increase
Genetic Manipulation
Post developmental RNA interference
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Caenorhabditis elegans
    sma-2
    Danio rerio
    smad2
    Homo sapiens
    SMAD2
    Mus musculus
    Smad2
    Rattus norvegicus
    Smad2

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
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    Homologues
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    UniProt
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    Internet
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