Drosophila melanogasterGenAge entry for SdhB (Drosophila melanogaster)

Gene information (ID: 593)

Symbol
SdhB
Aliases
CG3283; Dmel\CG3283; Ip; SDH; SDH-Ip; SDH-IP; sdhB; SDHb
Name
Succinate dehydrogenase B
Organism
Drosophila melanogaster (AnAge)
Known functions and activities
Succinate dehydrogenase B

Potential relevance to longevity and/or ageing

Observations
Mutant males are hypersensitive to oxygen and displays signs of premature ageing, including a 66% decrease in mean lifespan and a 17% decrease in maximum lifespan.
% change in max lifespan
Maximum male lifespan is 17% lower.
% change in avg or median lifespan
Average male lifespan is 66% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Mutation
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    sdhb
    Homo sapiens
    SDHB
    Mus musculus
    Sdhb
    Rattus norvegicus
    Sdhb

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
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    Homologues
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    UniProt
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    Internet
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