Saccharomyces cerevisiaeGenAge entry for SIR3 (Saccharomyces cerevisiae)

Gene information (ID: 607)

Symbol
SIR3
Aliases
CMT1; MAR2; STE8
Name
Silent information regulator
Organism
Saccharomyces cerevisiae (AnAge)
Known functions and activities
Silencing protein

Potential relevance to longevity and/or ageing

Observations
Mutants show a 20% decrease in mean lifespan.
% change in avg or median lifespan
Average lifespan is 20% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Mutation
Longevity Category
Necessary for fitness
Primary reference
    Observations
    Mean chronological lifespan strongly decreased in the a strain
    Lifespan Effect
    Decrease
    Genetic Manipulation
    Deletion
    Longevity Category
    Necessary for fitness
    Primary reference

      Homologs in other organisms

      Caenorhabditis elegans
      orc-1
      Danio rerio
      orc1
      Schizosaccharomyces pombe
      orc1

      External links

      Saccharomyces Genome Database
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (851163)
      Homologues
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      UniProt
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      Internet
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