Drosophila melanogasterGenAge entry for Rpd3 (Drosophila melanogaster)

Gene information (ID: 556)

Symbol
Rpd3
Aliases
CG7471; dHDAC-1; dHDAC1; DHDAC1; Dmel\CG7471; dmHDA401;
Name
CG7471-PA
Organism
Drosophila melanogaster (AnAge)
Known functions and activities
Regulates transcription and silencing

Potential relevance to longevity and/or ageing

Observations
Mutations extend lifespan by 33% in males and 52% in females.
% change in avg or median lifespan
Female lifespan is 52% higher; Male lifespan is 33% higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Saccharomyces cerevisiae is present as RPD3
    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as HDAC1
    GenDR gene manipulations
    • This gene is present as Rpd3
    • A homolog of this gene for Saccharomyces cerevisiae is present as RPD3
    CellAge
    • A homolog of this gene for Homo sapiens is present as HDAC1

    Homologs in other organisms

    Caenorhabditis elegans
    hda-1
    Danio rerio
    hdac1
    Homo sapiens
    HDAC1
    Mus musculus
    Gm10093
    Rattus norvegicus
    Hdac1l
    Saccharomyces cerevisiae
    RPD3
    Schizosaccharomyces pombe
    clr6

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (38565)
    Homologues
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    UniProt
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    Internet
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