Mus musculusGenAge entry for Rae1 (Mus musculus)

Gene information (ID: 537)

Symbol
Rae1
Aliases
41; MNRP; MNRP41; D2Ertd342e; 3230401I12Rik
Name
RAE1 RNA export 1 homolog (S. pombe)
Organism
Mus musculus (AnAge)
Known functions and activities
RNA export

Potential relevance to longevity and/or ageing

Observations
Haploinsufficiency of Bub3 and Rae1, but not haploinsufficiency of either gene by itself, reduces lifespan by 12% and appears to accelerate ageing.
Lifespan Effect
Decrease
Genetic Manipulation
Knockout
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as RAE1

    Homologs in other organisms

    Caenorhabditis elegans
    npp-17
    Danio rerio
    rae1
    Drosophila melanogaster
    Rae1
    Homo sapiens
    RAE1
    Rattus norvegicus
    Rae1
    Saccharomyces cerevisiae
    GLE2
    Schizosaccharomyces pombe
    rae1

    External links

    Mouse Genome Informatics
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (66679)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
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