Saccharomyces cerevisiaeGenAge entry for RPT6 (Saccharomyces cerevisiae)

Gene information (ID: 2018)

Symbol
RPT6
Aliases
CIM3; CRL3; SCB68; SUG1
Name
proteasome regulatory particle base subunit RPT6
Organism
Saccharomyces cerevisiae (AnAge)

Potential relevance to longevity and/or ageing

Observations
Rpt6 mutants exhibit reduced replicative lifespan.
% change in avg or median lifespan
Mean replicative lifespan is 63% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Mutation
Longevity Category
Necessary for fitness
Primary reference

    Homologs in other organisms

    Caenorhabditis elegans
    CELE_F56F11.4
    Danio rerio
    psmc5
    Drosophila melanogaster
    Rpt6R
    Homo sapiens
    PSMC5
    Mus musculus
    Psmc5
    Rattus norvegicus
    Psmc5
    Schizosaccharomyces pombe
    let1

    External links

    Saccharomyces Genome Database
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (852834)
    Homologues
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    UniProt
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    Internet
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