Saccharomyces cerevisiaeGenAge entry for RPT5 (Saccharomyces cerevisiae)

Gene information (ID: 2017)

Symbol
RPT5
Aliases
YTA1
Name
proteasome regulatory particle base subunit RPT5
Organism
Saccharomyces cerevisiae (AnAge)

Potential relevance to longevity and/or ageing

Observations
Rpt5 mutants exhibit reduced replicative lifespan.
% change in avg or median lifespan
Mean replicative lifespan is 85% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Mutation
Longevity Category
Necessary for fitness
Primary reference

    Homologs in other organisms

    Caenorhabditis elegans
    rpt-5
    Danio rerio
    psmc3
    Drosophila melanogaster
    Tbp-1
    Homo sapiens
    PSMC3
    Mus musculus
    Psmc3
    Rattus norvegicus
    Psmc3
    Schizosaccharomyces pombe
    tbp1

    External links

    Saccharomyces Genome Database
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (854284)
    Homologues
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    UniProt
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    Internet
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