Saccharomyces cerevisiaeGenAge entry for RPT3 (Saccharomyces cerevisiae)

Gene information (ID: 2016)

Symbol
RPT3
Aliases
YNT1; YTA2
Name
proteasome regulatory particle base subunit RPT3
Organism
Saccharomyces cerevisiae (AnAge)

Potential relevance to longevity and/or ageing

Observations
Rpt3 mutants exhibit reduced replicative lifespan.
% change in avg or median lifespan
Mean replicative lifespan is 55% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Mutation
Longevity Category
Necessary for fitness
Primary reference

    Homologs in other organisms

    Caenorhabditis elegans
    rpt-3
    Danio rerio
    psmc4
    Drosophila melanogaster
    Rpt3R
    Homo sapiens
    PSMC4
    Mus musculus
    Psmc4
    Rattus norvegicus
    Psmc4
    Schizosaccharomyces pombe
    rpt3

    External links

    Saccharomyces Genome Database
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (852003)
    Homologues
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    UniProt
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    Internet
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