Saccharomyces cerevisiaeGenAge entry for RPT2 (Saccharomyces cerevisiae)

Gene information (ID: 2015)

Symbol
RPT2
Aliases
YHS4; YTA5
Name
proteasome regulatory particle base subunit RPT2
Organism
Saccharomyces cerevisiae (AnAge)

Potential relevance to longevity and/or ageing

Observations
Rpt2 mutants exhibit reduced replicative lifespan.
% change in avg or median lifespan
Mean replicative lifespan is 68% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Mutation
Longevity Category
Necessary for fitness
Primary reference

    Homologs in other organisms

    Caenorhabditis elegans
    rpt-2
    Danio rerio
    psmc1b
    Drosophila melanogaster
    Pros26.4
    Homo sapiens
    PSMC1
    Mus musculus
    Psmc1
    Rattus norvegicus
    Psmc1
    Schizosaccharomyces pombe
    mts2

    External links

    Saccharomyces Genome Database
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (851557)
    Homologues
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    UniProt
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    Internet
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