Saccharomyces cerevisiaeGenAge entry for RPS18B (Saccharomyces cerevisiae)

Gene information (ID: 576)

Symbol
RPS18B
Name
ribosomal 40S subunit protein S18B
Organism
Saccharomyces cerevisiae (AnAge)
Known functions and activities
Protein component of the small (40S) ribosomal subunit

Potential relevance to longevity and/or ageing

Observations
Deletion of RPS18B increases yeast chronological lifespan.
Lifespan Effect
Increase
Genetic Manipulation
Deletion
Longevity Category
Anti-Longevity
Primary reference
    Observations
    Deletion of both RPS18A and RPS18B paralogs increased replicative lifespan by 15%.
    % change in avg or median lifespan
    Replicative lifespan is 15% higher.
    Lifespan Effect
    Increase
    Genetic Manipulation
    Deletion
    Longevity Category
    Anti-Longevity
    Primary reference

      Homologs in other organisms

      Caenorhabditis elegans
      rps-18
      Danio rerio
      rps18
      Drosophila melanogaster
      RpS18
      Homo sapiens
      RPS18
      Mus musculus
      Gm10260
      Rattus norvegicus
      LOC100912024
      Schizosaccharomyces pombe
      rps18a

      External links

      Saccharomyces Genome Database
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (854982)
      Homologues
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      UniProt
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      Internet
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