Saccharomyces cerevisiaeGenAge entry for ROM2 (Saccharomyces cerevisiae)

Gene information (ID: 554)

Symbol
ROM2
Name
GDP/GTP exchange protein (GEP) for Rho1p and Rho2p
Organism
Saccharomyces cerevisiae (AnAge)
Known functions and activities
Activator of protein kinase C

Potential relevance to longevity and/or ageing

Observations
Deletion increased mean replicative lifespan by about 30%.
% change in avg or median lifespan
Average replicative lifespan is about 30% higher.
Lifespan Effect
Increase
Genetic Manipulation
Deletion
Longevity Category
Anti-Longevity
Primary reference
    Observations
    Replicative lifespan increased by 50% in the alpha strain and 20% in a strain
    % change in avg or median lifespan
    Replicative lifespan is 20-50% higher.
    Lifespan Effect
    Increase
    Genetic Manipulation
    Deletion
    Longevity Category
    Anti-Longevity
    Primary reference

      Homologs in other organisms

      Danio rerio
      arhgef18a

      External links

      Saccharomyces Genome Database
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (851086)
      Homologues
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      UniProt
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      Internet
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