Saccharomyces cerevisiaeGenAge entry for RAD57 (Saccharomyces cerevisiae)

Gene information (ID: 535)

Symbol
RAD57
Name
Rad57p
Organism
Saccharomyces cerevisiae (AnAge)
Known functions and activities
Protein that stimulates strand exchange by stabilizing the binding of Rad51p to single-stranded DNA

Potential relevance to longevity and/or ageing

Observations
Mutations result in a 40% reduced lifespan.
% change in avg or median lifespan
Lifespan is 40% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Mutations
Longevity Category
Necessary for fitness
Primary reference

    In other databases

    LongevityMap
    • A homolog of this gene for Homo sapiens is present as XRCC3

    Homologs in other organisms

    Danio rerio
    rad51d
    Homo sapiens
    XRCC3
    Schizosaccharomyces pombe
    rhp57

    External links

    Saccharomyces Genome Database
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (851567)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar