Mus musculusGenAge entry for Ppm1d (Mus musculus)

Gene information (ID: 515)

Symbol
Ppm1d
Aliases
Wip1; AV338790
Name
protein phosphatase 1D magnesium-dependent, delta isoform
Organism
Mus musculus (AnAge)
Known functions and activities
May contribute to oncogenesis through functional inactivation of p53

Potential relevance to longevity and/or ageing

Observations
Knockout mice are resistant to spontaneous tumors but show a modest reduction in lifespan and reduced body weight.
Lifespan Effect
Decrease
Genetic Manipulation
Knockout
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as PPM1D
    CellAge
    • A homolog of this gene for Homo sapiens is present as PPM1D

    Homologs in other organisms

    Danio rerio
    ppm1da
    Homo sapiens
    PPM1D
    Rattus norvegicus
    Ppm1d

    External links

    Mouse Genome Informatics
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (53892)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
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