Drosophila melanogasterGenAge entry for Pka-C1 (Drosophila melanogaster)

Gene information (ID: 507)

Symbol
Pka-C1
Aliases
6353; BG02142; C; CdkA; CG4379; Cos; Cos-1; cos1; Cos1; Dc0
Name
cAMP-dependent protein kinase 1
Organism
Drosophila melanogaster (AnAge)
Known functions and activities
cAMP-dependent protein kinase 1

Potential relevance to longevity and/or ageing

Observations
PKA-overexpressing flies (hsPKA*/+) have an about 30% extended maximum lifespan.
% change in max lifespan
Maximum lifespan is approximately 30% higher.
Lifespan Effect
Increase
Genetic Manipulation
Overexpression
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    Caenorhabditis elegans
    kin-1
    Danio rerio
    prkacbb
    Homo sapiens
    PRKACG
    Mus musculus
    Prkaca
    Rattus norvegicus
    Prkacb

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (34284)
    Homologues
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    UniProt
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    Internet
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