Drosophila melanogasterGenAge entry for POSH (Drosophila melanogaster)

Gene information (ID: 514)

Symbol
POSH
Aliases
155116_at; BEST:GM09451; CG4909; Dmel\CG4909; dPOSH; DP
Name
Plenty of SH3s
Organism
Drosophila melanogaster (AnAge)

Potential relevance to longevity and/or ageing

Observations
Neural-specific overexpression of DPOSH extends the mean lifespan of adult flies by 14%.
% change in avg or median lifespan
Average lifespan is 14% higher.
Lifespan Effect
Increase
Genetic Manipulation
Overexpression
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    Caenorhabditis elegans
    CELE_Y44E3A.4
    Danio rerio
    sh3rf1
    Homo sapiens
    SH3RF1
    Mus musculus
    Sh3rf1
    Rattus norvegicus
    Sh3rf1

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (36990)
    Homologues
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    UniProt
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    Internet
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