Saccharomyces cerevisiaeGenAge entry for PHB1 (Saccharomyces cerevisiae)

Gene information (ID: 504)

Symbol
PHB1
Name
Phb1p
Organism
Saccharomyces cerevisiae (AnAge)

Potential relevance to longevity and/or ageing

Observations
Deletion results in a reduction in mean and maximum replicative lifespan and a defect in mitochondrial membrane potential.
Lifespan Effect
Decrease
Genetic Manipulation
Deletion
Longevity Category
Necessary for fitness
Primary reference
    Observations
    Replicative lifespan decreased by 20%
    % change in avg or median lifespan
    Replicative lifespan is 20% lower.
    Lifespan Effect
    Decrease
    Genetic Manipulation
    Deletion
    Longevity Category
    Pro-Longevity
    Primary reference

      In other databases

      GenAge model organism genes
      • A homolog of this gene for Caenorhabditis elegans is present as phb-1

      Homologs in other organisms

      Caenorhabditis elegans
      phb-1
      Danio rerio
      phb
      Drosophila melanogaster
      l(2)37Cc
      Homo sapiens
      PHB
      Mus musculus
      Phb
      Rattus norvegicus
      RGD1561288
      Schizosaccharomyces pombe
      phb1

      External links

      Saccharomyces Genome Database
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (853033)
      Homologues
      Search HomoloGene
      UniProt
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      Internet
      Search Google or Search Google Scholar