Drosophila melanogasterGenAge entry for Naam (Drosophila melanogaster)

Gene information (ID: 871)

Symbol
Naam
Aliases
AAM52663; anon-WO0172774.59; anon-WO0172774.60; CG312
Name
Naam gene product from transcript Naam-RA
Organism
Drosophila melanogaster (AnAge)

Potential relevance to longevity and/or ageing

Observations
An increase in mean and maximal lifespan was observed for both male and female flies. The lifespan extension was reversed in Sir2 mutants, suggesting that the extension is Sir2 dependent.
% change in max lifespan
Maximum lifespan is up to 30% higher.
% change in avg or median lifespan
Average lifespan is up to 30% higher; Maximum lifespan is up to 30% higher.
Lifespan Effect
Increase
Genetic Manipulation
Overexpression
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Saccharomyces cerevisiae is present as PNC1
    GenDR gene manipulations
    • A homolog of this gene for Saccharomyces cerevisiae is present as PNC1

    Homologs in other organisms

    Caenorhabditis elegans
    pnc-2
    Saccharomyces cerevisiae
    PNC1
    Schizosaccharomyces pombe
    pnc1

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (42348)
    Homologues
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    UniProt
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    Internet
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