Saccharomyces cerevisiaeGenAge entry for NDE2 (Saccharomyces cerevisiae)

Gene information (ID: 456)

Symbol
NDE2
Aliases
NDH2
Name
NADH-ubiquinone reductase (H(+)-translocating) NDE2
Organism
Saccharomyces cerevisiae (AnAge)
Known functions and activities
Mitochondrial electron transport chain

Potential relevance to longevity and/or ageing

Observations
Overexpression of Nde1 and Nde2 resulted in a longer replicative lifespan (20-25%) on 2% glucose, but not on 0.5% glucose.
% change in avg or median lifespan
Replicative lifespan is 20-25% higher.
Lifespan Effect
Increase
Genetic Manipulation
Overexpression
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenDR gene manipulations
    • This gene is present as NDE2

    Homologs in other organisms

    Schizosaccharomyces pombe
    SPAC3A11.07

    External links

    Saccharomyces Genome Database
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (851474)
    Homologues
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    UniProt
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    Internet
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