Drosophila melanogasterGenAge entry for LBR (Drosophila melanogaster)

Gene information (ID: 863)

Symbol
LBR
Aliases
CG17952; dLBR; Dmel\CG17952
Name
Lamin B receptor
Organism
Drosophila melanogaster (AnAge)

Potential relevance to longevity and/or ageing

Observations
Overexpression of lamin B receptor in the adult muscle and in the abdominal fat body, resulted in a 54% and respectively 46% reduction of mean life span.
Lifespan Effect
Decrease
Genetic Manipulation
Overexpression
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenDR gene expression
    • A homolog of this gene for Mus musculus is present as Dhcr7

    Homologs in other organisms

    Danio rerio
    dhcr7
    Homo sapiens
    DHCR7
    Mus musculus
    Dhcr7
    Rattus norvegicus
    Dhcr7

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (37482)
    Homologues
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    UniProt
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    Internet
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