Drosophila melanogasterGenAge entry for Keap1 (Drosophila melanogaster)

Gene information (ID: 859)

Symbol
Keap1
Aliases
CG3962; dkeap1; dKeap1; dKEAP1; Dmel\CG3962; keap1; KEAP
Name
CG3962 gene product from transcript CG3962-RA
Organism
Drosophila melanogaster (AnAge)

Potential relevance to longevity and/or ageing

Observations
Male keap1 heterozygotes lived significantly longer than their otherwise genetically identical siblings. Female keap1 heterozygotes did not show significant differences in either paraquat resistance or longevity.
% change in avg or median lifespan
Median male lifespan was 8%-10% higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutations
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    keap1a
    Homo sapiens
    KEAP1
    Mus musculus
    Keap1
    Rattus norvegicus
    Keap1

    External links

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    Entrez Gene
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    Internet
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