Saccharomyces cerevisiaeGenAge entry for KGD1 (Saccharomyces cerevisiae)

Gene information (ID: 1078)

Symbol
KGD1
Aliases
OGD1
Name
alpha-KetoGlutarate Dehydrogenase
Organism
Saccharomyces cerevisiae (AnAge)

Potential relevance to longevity and/or ageing

Observations
Mean replicative lifespan decreased in the alpha and a strain
Lifespan Effect
Decrease
Genetic Manipulation
Deletion
Longevity Category
Necessary for fitness
Primary reference
    Observations
    Mean chronological lifespan decreased in the a strain by more than 50%
    % change in avg or median lifespan
    Mean chronological lifespan is more than 50% lower.
    Lifespan Effect
    Decrease
    Genetic Manipulation
    Deletion
    Longevity Category
    Necessary for fitness
    Primary reference

      In other databases

      GenAge model organism genes
      • A homolog of this gene for Caenorhabditis elegans is present as ogdh-1
      • A homolog of this gene for Schizosaccharomyces pombe is present as SPBC3H7.03c

      Homologs in other organisms

      Caenorhabditis elegans
      T22B11.5
      Danio rerio
      ogdhl
      Drosophila melanogaster
      CG18170
      Homo sapiens
      OGDHL
      Mus musculus
      Ogdhl
      Rattus norvegicus
      Ogdhl
      Schizosaccharomyces pombe
      kgd1

      External links

      Saccharomyces Genome Database
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (854681)
      Homologues
      Search HomoloGene
      UniProt
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      Internet
      Search Google or Search Google Scholar