Saccharomyces cerevisiaeGenAge entry for ISM1 (Saccharomyces cerevisiae)

Gene information (ID: 1706)

Symbol
ISM1
Name
Isoleucyl tRNA Synthetase of Mitochondria
Organism
Saccharomyces cerevisiae (AnAge)

Potential relevance to longevity and/or ageing

Observations
Replicative lifespan increased by 15% in the alpha strain
% change in avg or median lifespan
Replicative lifespan is 15% higher.
Lifespan Effect
Increase
Genetic Manipulation
Deletion
Longevity Category
Anti-Longevity
Primary reference
    Observations
    Replicative lifespan decreased by 20% in the a strain
    % change in avg or median lifespan
    Replicative lifespan is 20% lower.
    Lifespan Effect
    Decrease
    Genetic Manipulation
    Deletion
    Longevity Category
    Necessary for fitness
    Primary reference

      Homologs in other organisms

      Caenorhabditis elegans
      iars-2
      Danio rerio
      iars2
      Drosophila melanogaster
      CG5414
      Homo sapiens
      IARS2
      Mus musculus
      Iars2
      Schizosaccharomyces pombe
      ism1

      External links

      Saccharomyces Genome Database
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (856067)
      Homologues
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      UniProt
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      Internet
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