Saccharomyces cerevisiaeGenAge entry for IDH2 (Saccharomyces cerevisiae)

Gene information (ID: 358)

Symbol
IDH2
Name
Idh2p
Organism
Saccharomyces cerevisiae (AnAge)
Known functions and activities
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase

Potential relevance to longevity and/or ageing

Observations
Deletion increased the mean replicative lifespan by about 30%.
% change in avg or median lifespan
Replicative lifespan is about 30% higher.
Lifespan Effect
Increase
Genetic Manipulation
Deletion
Longevity Category
Anti-Longevity
Primary reference
    Observations
    Replicative lifespan increased by 20% in the alpha strain and in a strain
    % change in avg or median lifespan
    Replicative lifespan is 20% higher.
    Lifespan Effect
    Increase
    Genetic Manipulation
    Deletion
    Longevity Category
    Anti-Longevity
    Primary reference
      Observations
      Replicative lifespan increased by 20% in the alpha strain and in a strain
      % change in avg or median lifespan
      Replicative lifespan is 20% higher.
      Lifespan Effect
      Increase
      Genetic Manipulation
      Deletion
      Longevity Category
      Anti-Longevity
      Primary reference

        In other databases

        GenAge model organism genes
        • A homolog of this gene for Caenorhabditis elegans is present as idha-1

        Homologs in other organisms

        Caenorhabditis elegans
        F43G9.1
        Danio rerio
        idh3a
        Drosophila melanogaster
        CG32026
        Homo sapiens
        IDH3A
        Mus musculus
        Idh3a
        Rattus norvegicus
        Idh3a
        Schizosaccharomyces pombe
        idh2

        External links

        Saccharomyces Genome Database
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        Ensembl
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        Entrez Gene
        View on Entrez Gene database (854303)
        Homologues
        Search HomoloGene
        UniProt
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        Internet
        Search Google or Search Google Scholar