Mus musculusGenAge entry for Htt (Mus musculus)

Gene information (ID: 820)

Symbol
Htt
Aliases
Hd; Hdh; IT15; AI256365; C430023I11Rik
Name
Huntingtin
Organism
Mus musculus (AnAge)

Potential relevance to longevity and/or ageing

Observations
Deletion of the Polyglutamine stretch in Htt extends mean and maximal lifespan.
% change in max lifespan
Maximum lifespan is 17% higher.
% change in avg or median lifespan
Median lifespan is 18% higher.
Lifespan Effect
Increase
Genetic Manipulation
Deletion of a region
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as HTT

    Homologs in other organisms

    Drosophila melanogaster
    htt
    Danio rerio
    htt
    Homo sapiens
    HTT
    Rattus norvegicus
    Htt

    External links

    Mouse Genome Informatics
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (15194)
    Homologues
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    UniProt
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    Internet
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