Saccharomyces cerevisiaeGenAge entry for HST2 (Saccharomyces cerevisiae)

Gene information (ID: 353)

Symbol
HST2
Name
Hst2p
Organism
Saccharomyces cerevisiae (AnAge)
Known functions and activities
Cytoplasmic member of the silencing information regulator 2 (Sir2) family

Potential relevance to longevity and/or ageing

Observations
Overexpression results in replicative lifespan extension.
Lifespan Effect
Increase
Genetic Manipulation
Overexpression
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Caenorhabditis elegans is present as sir-2.1
    • A homolog of this gene for Drosophila melanogaster is present as Sirt2
    GenDR gene manipulations
    • A homolog of this gene for Caenorhabditis elegans is present as sir-2.1
    • This gene is present as HST2

    Homologs in other organisms

    Caenorhabditis elegans
    sir-2.1
    Danio rerio
    sirt3
    Drosophila melanogaster
    Sirt2
    Homo sapiens
    SIRT2
    Mus musculus
    Sirt3
    Rattus norvegicus
    Sirt2
    Schizosaccharomyces pombe
    hst2

    External links

    Saccharomyces Genome Database
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (856092)
    Homologues
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    UniProt
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    Internet
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