Saccharomyces cerevisiaeGenAge entry for HIR2 (Saccharomyces cerevisiae)

Gene information (ID: 1069)

Symbol
HIR2
Aliases
SPT1
Name
HIstone Regulation
Organism
Saccharomyces cerevisiae (AnAge)

Potential relevance to longevity and/or ageing

Observations
Mean replicative lifespan decreased in the alpha and a strain
Lifespan Effect
Decrease
Genetic Manipulation
Deletion
Longevity Category
Necessary for fitness
Primary reference
    Observations
    Inactivation of any component of the Hir complex extended the median replicative life span by 25%-35%.
    % change in avg or median lifespan
    Replicative lifespan is 25-35% higher.
    Lifespan Effect
    Increase
    Genetic Manipulation
    Deletion
    Longevity Category
    Anti-Longevity
    Primary reference

      Homologs in other organisms

      Drosophila melanogaster
      Hira
      Homo sapiens
      HIRA
      Schizosaccharomyces pombe
      slm9

      External links

      Saccharomyces Genome Database
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (854203)
      Homologues
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      UniProt
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      Internet
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