Saccharomyces cerevisiaeGenAge entry for HIR1 (Saccharomyces cerevisiae)

Gene information (ID: 1068)

Symbol
HIR1
Name
HIstone Regulation
Organism
Saccharomyces cerevisiae (AnAge)

Potential relevance to longevity and/or ageing

Observations
Mean replicative lifespan decreased in the alpha and a strain
Lifespan Effect
Decrease
Genetic Manipulation
Deletion
Longevity Category
Necessary for fitness
Primary reference
    Observations
    Inactivation of any component of the Hir complex extended the median replicative life span by 25%-35%.
    % change in avg or median lifespan
    Replicative lifespan is 25-35% higher.
    Lifespan Effect
    Increase
    Genetic Manipulation
    Deletion
    Longevity Category
    Anti-Longevity
    Primary reference

      Homologs in other organisms

      Caenorhabditis elegans
      K10D2.1
      Danio rerio
      hira
      Mus musculus
      Hira
      Rattus norvegicus
      LOC100911837
      Schizosaccharomyces pombe
      hip1

      External links

      Saccharomyces Genome Database
      Search
      Ensembl
      Search
      Entrez Gene
      View on Entrez Gene database (852275)
      Homologues
      Search HomoloGene
      UniProt
      Search
      Internet
      Search Google or Search Google Scholar