Drosophila melanogasterGenAge entry for Gnmt (Drosophila melanogaster)

Gene information (ID: 2096)

Symbol
Gnmt
Name
Glycine N-methyltransferase
Organism
Drosophila melanogaster (AnAge)

Potential relevance to longevity and/or ageing

Observations
Gnmt acts to buffer systemic S-adenosyl-methionine (SAM) synthesis. Overexpression of Gnmt resulted in an increase in lifespan, dependant on increased Gnmt enzymatic activity.
Lifespan Effect
Increase
Genetic Manipulation
Overexpression
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    gnmt
    Homo sapiens
    GNMT
    Mus musculus
    Gnmt
    Rattus norvegicus
    LOC100911564

    External links

    FlyBase
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    Entrez Gene
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    Homologues
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    UniProt
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    Internet
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