Mus musculusGenAge entry for Ghrh (Mus musculus)

Gene information (ID: 1848)

Symbol
Ghrh
Aliases
Ghrf
Name
growth hormone releasing hormone
Organism
Mus musculus (AnAge)

Potential relevance to longevity and/or ageing

Observations
Ghrh knockout mice live 46% longer than controls. Females live 43% longer and males 51% longer, though maximum lifespan was only increased (by 33%) in females. Both males and females and markedly smaller than controls.
% change in max lifespan
Female maximum lifespan is 33% higher.
% change in avg or median lifespan
Median lifespan is 46% longer.
Lifespan Effect
Increase
Genetic Manipulation
Knockout
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as GHRH

    Homologs in other organisms

    Danio rerio
    ghrh
    Homo sapiens
    GHRH
    Rattus norvegicus
    Ghrh

    External links

    Mouse Genome Informatics
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (14601)
    Homologues
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    UniProt
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    Internet
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