Mus musculusGenAge entry for GMFB (Mus musculus)

Gene information (ID: 2153)

Symbol
GMFB
Name
glia maturation factor beta
Organism
Mus musculus (AnAge)

Potential relevance to longevity and/or ageing

Observations
Mice overexpressing human GMFB (GMFB-Tg) had a 6% decrease in mean lifespan compared to wild type mice. In addition GMFB-Tg demonstrated signs of premature ageing including hair greying and loss, skin atrophy and spinal curvature. Some of the GMFB-Tg mice died within 60 weeks.
% change in avg or median lifespan
Mean lifespan is 6% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Overexpression
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Homo sapiens
    GMFB
    Homo sapiens
    GMFB
    Homo sapiens
    GMFB

    External links

    Mouse Genome Informatics
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    Entrez Gene
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    UniProt
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    Internet
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