Saccharomyces cerevisiaeGenAge entry for GCN5 (Saccharomyces cerevisiae)

Gene information (ID: 295)

Symbol
GCN5
Aliases
AAS104; ADA4; SWI9
Name
Histone acetyltransferase
Organism
Saccharomyces cerevisiae (AnAge)

Potential relevance to longevity and/or ageing

Observations
Deletion suppressed extension of replicative lifespan.
Lifespan Effect
Decrease
Genetic Manipulation
Deletion
Longevity Category
Necessary for fitness
Primary reference
    Observations
    Strongly reduced chronological lifespan
    Lifespan Effect
    Decrease
    Genetic Manipulation
    Deletion
    Longevity Category
    Necessary for fitness
    Primary reference
      Observations
      Mean chronological lifespan strongly decreased in the a strain
      Lifespan Effect
      Decrease
      Genetic Manipulation
      Deletion
      Longevity Category
      Necessary for fitness
      Primary reference
        Observations
        Mean chronological lifespan decreased in the a strain by more than 50%
        % change in avg or median lifespan
        Mean chronological lifespan is more than 50% lower.
        Lifespan Effect
        Decrease
        Genetic Manipulation
        Deletion
        Longevity Category
        Necessary for fitness
        Primary reference

          Homologs in other organisms

          Caenorhabditis elegans
          pcaf-1
          Rattus norvegicus
          Kat2a
          Schizosaccharomyces pombe
          gcn5

          External links

          Saccharomyces Genome Database
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          Ensembl
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          Entrez Gene
          View on Entrez Gene database (853167)
          Homologues
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          UniProt
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          Internet
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