Mus musculusGenAge entry for Fgf21 (Mus musculus)

Gene information (ID: 1800)

Symbol
Fgf21
Name
fibroblast growth factor 21
Organism
Mus musculus (AnAge)

Potential relevance to longevity and/or ageing

Observations
Transgenic overexpression of Fgf21 in hepatocytes increases average (by 36%) and maximum (by at least 16%) lifespan.
% change in max lifespan
Maximum lifespan is 16% higher.
% change in avg or median lifespan
Average lifespan is 14% higher.
Lifespan Effect
Increase
Genetic Manipulation
Overexpression
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as FGF21

    Homologs in other organisms

    Homo sapiens
    FGF21
    Rattus norvegicus
    Fgf21

    External links

    Mouse Genome Informatics
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (56636)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar