Saccharomyces cerevisiaeGenAge entry for FIS1 (Saccharomyces cerevisiae)

Gene information (ID: 283)

Symbol
FIS1
Aliases
MDV2
Name
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
Organism
Saccharomyces cerevisiae (AnAge)
Known functions and activities
Mitochondrial outer membrane protein involved in membrane fission

Potential relevance to longevity and/or ageing

Observations
Deletion prolonged the lifespan and improved the fitness of old mother cells.
Lifespan Effect
Increase
Genetic Manipulation
Deletion
Longevity Category
Anti-Longevity
Primary reference
    Observations
    Mean chronological lifespan strongly decreased in the a strain
    Lifespan Effect
    Decrease
    Genetic Manipulation
    Deletion
    Longevity Category
    Necessary for fitness
    Primary reference

      Homologs in other organisms

      Caenorhabditis elegans
      fis-1
      Danio rerio
      uncharacterized_E9QG
      Drosophila melanogaster
      Fis1
      Homo sapiens
      FIS1
      Mus musculus
      Fis1
      Rattus norvegicus
      Fis1
      Schizosaccharomyces pombe
      fis1

      External links

      Saccharomyces Genome Database
      Search
      Ensembl
      Search
      Entrez Gene
      View on Entrez Gene database (854745)
      Homologues
      Search HomoloGene
      UniProt
      Search
      Internet
      Search Google or Search Google Scholar