Mus musculusGenAge entry for Ercc2 (Mus musculus)

Gene information (ID: 222)

Symbol
Ercc2
Aliases
XPD; CXPD; Ercc-2; AA407812; AU020867; AW240756
Name
Excision repair cross-complementing rodent repair deficiency, complementation group 2
Organism
Mus musculus (AnAge)
Known functions and activities
Helicase involved in DNA repair and condensation

Potential relevance to longevity and/or ageing

Observations
Mutations increase cancer incidence and appear to accelerate ageing.
Lifespan Effect
Decrease
Genetic Manipulation
Mutations
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as ERCC2
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as ERCC2

    Homologs in other organisms

    Caenorhabditis elegans
    Y50D7A.11
    Danio rerio
    ercc2
    Drosophila melanogaster
    Xpd
    Homo sapiens
    ERCC2
    Rattus norvegicus
    Ercc2
    Saccharomyces cerevisiae
    RAD3
    Schizosaccharomyces pombe
    rad15

    External links

    Mouse Genome Informatics
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (13871)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar