Mus musculusGenAge entry for Efemp1 (Mus musculus)

Gene information (ID: 209)

Symbol
Efemp1
Name
Epidermal growth factor-containing fibulin-like extracellular matrix protein 1
Organism
Mus musculus (AnAge)
Known functions and activities
Extracellular matrix (ECM) protein of unknown function

Potential relevance to longevity and/or ageing

Observations
Knockout mice exhibited an early onset of ageing-associated phenotypes including a 20% shorted median lifespan and 30% shorter maximum lifespan, decreased body mass, lordokyphosis, reduced hair growth, and atrophy.
% change in max lifespan
Maximum lifespan is 30% lower.
% change in avg or median lifespan
Median lifespan is 20% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Knockout
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as EFEMP1
    GenAge microarray genes
    • A homolog of this gene for Homo sapiens is present as EFEMP1
    CellAge gene expression
    • A homolog of this gene for Homo sapiens is present as EFEMP1

    Homologs in other organisms

    Caenorhabditis elegans
    fbl-1
    Danio rerio
    EFEMP1 (1 of many)
    Danio rerio
    EFEMP1 (1 of many)
    Drosophila melanogaster
    CG31999
    Homo sapiens
    EFEMP1
    Rattus norvegicus
    Efemp1

    External links

    Mouse Genome Informatics
    Search
    Ensembl
    Search
    Entrez Gene
    View on Entrez Gene database (216616)
    Homologues
    Search HomoloGene
    UniProt
    Search
    Internet
    Search Google or Search Google Scholar