Saccharomyces cerevisiaeGenAge entry for EUG1 (Saccharomyces cerevisiae)

Gene information (ID: 1229)

Symbol
EUG1
Name
ER protein Unnecessary for Growth
Organism
Saccharomyces cerevisiae (AnAge)

Potential relevance to longevity and/or ageing

Observations
Deletion of eug1, a target of the unfolded protein response signaling, increases replicative lifespan.
% change in avg or median lifespan
Mean lifespan is 11% higher.
Lifespan Effect
Increase
Genetic Manipulation
Deletion
Longevity Category
Anti-Longevity
Primary reference
    Observations
    Mean chronological lifespan decreased in the a strain
    Lifespan Effect
    Decrease
    Genetic Manipulation
    Deletion
    Longevity Category
    Necessary for fitness
    Primary reference

      In other databases

      GenDR gene expression
      • A homolog of this gene for Mus musculus is present as Pdia3

      Homologs in other organisms

      Caenorhabditis elegans
      C14B9.2
      Danio rerio
      pdia3
      Drosophila melanogaster
      ERp60
      Homo sapiens
      PDIA3
      Mus musculus
      Pdia3
      Rattus norvegicus
      Pdia3
      Schizosaccharomyces pombe
      SPAC1F5.02

      External links

      Saccharomyces Genome Database
      Search
      Ensembl
      Search
      Entrez Gene
      View on Entrez Gene database (852130)
      Homologues
      Search HomoloGene
      UniProt
      Search
      Internet
      Search Google or Search Google Scholar