Saccharomyces cerevisiaeGenAge entry for DOT1 (Saccharomyces cerevisiae)

Gene information (ID: 1918)

Symbol
DOT1
Aliases
KMT4; PCH1
Name
histone methyltransferase DOT1
Organism
Saccharomyces cerevisiae (AnAge)

Potential relevance to longevity and/or ageing

Observations
Deletion of histone methyltransferase DOT1 results in an decreased replicative lifespan.
% change in avg or median lifespan
Replicative lifespan is 24% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Deletion
Longevity Category
Necessary for fitness
Primary reference

    Homologs in other organisms

    No homologs found

    External links

    Saccharomyces Genome Database
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (852050)
    Homologues
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    UniProt
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    Internet
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