Drosophila melanogasterGenAge entry for Cdk5 (Drosophila melanogaster)

Gene information (ID: 108)

Symbol
Cdk5
Aliases
cdk5; CDK5; CG8203; DmCdk5; Dmel\CG8203
Name
Cyclin-dependent kinase 5
Organism
Drosophila melanogaster (AnAge)
Known functions and activities
Cell cycle

Potential relevance to longevity and/or ageing

Observations
Loss-of-function mutations result in defective axon guidance, age-dependent behavioral deficits and reduced lifespan by about one third.
% change in avg or median lifespan
Lifespan is about one-third lower.
Lifespan Effect
Decrease
Genetic Manipulation
Mutation
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    Caenorhabditis elegans
    cdk-5
    Danio rerio
    cdk5
    Homo sapiens
    CDK5
    Mus musculus
    Cdk5
    Rattus norvegicus
    Cdk5

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (36727)
    Homologues
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    UniProt
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    Internet
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