Saccharomyces cerevisiaeGenAge entry for CHD1 (Saccharomyces cerevisiae)

Gene information (ID: 1360)

Symbol
CHD1
Name
Chromatin organization modifier, Helicase, and DNA-binding domains
Organism
Saccharomyces cerevisiae (AnAge)

Potential relevance to longevity and/or ageing

Observations
Deletion of CHD1 in yeast extends replicative lifespan by 14%.
% change in avg or median lifespan
Median replicative lifespan is 14% higher.
Lifespan Effect
Increase
Genetic Manipulation
Deletion
Longevity Category
Anti-Longevity
Primary reference
    Observations
    Mean chronological lifespan decreased in the a strain by less than 50% but more than 15%
    % change in avg or median lifespan
    Mean chronological lifespan is 15%-50% lower.
    Lifespan Effect
    Decrease
    Genetic Manipulation
    Deletion
    Longevity Category
    Necessary for fitness
    Primary reference

      Homologs in other organisms

      Caenorhabditis elegans
      chd-1
      Danio rerio
      uncharacterized_F1Q4
      Drosophila melanogaster
      Chd1
      Homo sapiens
      CHD2
      Mus musculus
      Chd1
      Rattus norvegicus
      Chd1
      Schizosaccharomyces pombe
      hrp1

      External links

      Saccharomyces Genome Database
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (856911)
      Homologues
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      UniProt
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      Internet
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