Caenorhabditis elegansGenAge entry for C11H1.3 (Caenorhabditis elegans)

Gene information (ID: 60)

Symbol
C11H1.3
Name
Protein C11H1.3
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
E3 ubiquitin ligase

Potential relevance to longevity and/or ageing

Observations
RNA interference decreased median lifespan by 10% in wild type animals, 14% in a daf-2 background and 41% in daf-2/daf-16 double mutants.
% change in avg or median lifespan
Median lifespan is 10% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    rnf157
    Drosophila melanogaster
    CG9941-RA
    Homo sapiens
    MGRN1
    Mus musculus
    Rnf157
    Rattus norvegicus
    LOC688272

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (181537)
    Homologues
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    UniProt
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    Internet
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