Mus musculusGenAge entry for Bax (Mus musculus)

Gene information (ID: 40)

Symbol
Bax
Name
Bcl2-associated X protein
Organism
Mus musculus (AnAge)
Known functions and activities
Apoptosis

Potential relevance to longevity and/or ageing

Observations
Inactivation extended fertile potential and minimized age-related health problems, including bone and muscle loss, excess fat deposition, alopecia, cataracts, deafness, increased anxiety, and selective attention deficit. It did not extend lifespan.
Lifespan Effect
Increase
Genetic Manipulation
Knockout
Primary reference

    In other databases

    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as BAX
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as BAX

    Homologs in other organisms

    Danio rerio
    baxa
    Homo sapiens
    BAX
    Rattus norvegicus
    Bax

    External links

    Mouse Genome Informatics
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (12028)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
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