Drosophila melanogasterGenAge entry for Atg1 (Drosophila melanogaster)

Gene information (ID: 1908)

Symbol
Atg1
Name
Autophagy-specific gene 1
Organism
Drosophila melanogaster (AnAge)

Potential relevance to longevity and/or ageing

Observations
Adult-onset, neuronal-specific upregulation of Atg1 results in increased median and maximum lifespan in female flies.
% change in avg or median lifespan
Median lifespan is up to 25% higher.
Lifespan Effect
Increase
Genetic Manipulation
Overexpression
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Caenorhabditis elegans is present as unc-51
    • A homolog of this gene for Saccharomyces cerevisiae is present as ATG1
    GenDR gene manipulations
    • A homolog of this gene for Caenorhabditis elegans is present as unc-51
    • A homolog of this gene for Saccharomyces cerevisiae is present as ATG1
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as ULK1

    Homologs in other organisms

    Caenorhabditis elegans
    unc-51
    Danio rerio
    ulk1b
    Homo sapiens
    ULK1
    Mus musculus
    Ulk1
    Rattus norvegicus
    Ulk1
    Saccharomyces cerevisiae
    ATG1
    Schizosaccharomyces pombe
    atg1

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (39454)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar