Drosophila melanogasterGenAge entry for Akt1 (Drosophila melanogaster)

Gene information (ID: 832)

Symbol
Akt1
Aliases
akt; Akt; AKT; Akt/PKB; AKT/PKB; akt1; AKT1; Akt1|PKB; CG4
Name
CG4006 gene product from transcript CG4006-RA
Organism
Drosophila melanogaster (AnAge)

Potential relevance to longevity and/or ageing

Observations
RNA interference of Akt in intestinal stem cells, results in impaired regeneration of the intestinal epithelium and are shorten lifespan.
% change in avg or median lifespan
Average male lifespan is 11.4% lower; Average female lifespan is 7.4% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    Caenorhabditis elegans
    akt-2
    Danio rerio
    akt2l
    Homo sapiens
    AKT2
    Mus musculus
    Akt2
    Rattus norvegicus
    Akt2
    Schizosaccharomyces pombe
    sck1

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (41957)
    Homologues
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    UniProt
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    Internet
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